Cured
豆瓣
How the Berlin Patients Defeated HIV and Forever Changed Medical Science
Nathalia Holt
简介
“Nathalia Holt presents a thorough account of the research that provides scientists with hope that a cure will one day be achievable... and her empathy shines through in her prose. This is as important a social history as it is a medical document.”—The Daily Beast
Two patients—each known in medical history as the Berlin Patient—were cured of the HIV virus. The two patients’ disparate cures came twelve years apart, but Nathalia Holt, an award-winning scientist at the forefront of HIV research, connects the molecular dots of these cases for the first time.
Scientists are known to maintain a professional distance from those they study, but sometimes scientists are not just investigators, they are caregivers, too. Cured illustrates that even in the era of high-tech and big pharma, the way doctors and patients communicate remains a critical ingredient in the advance of this science. Holt offers a kind of hope that the thirty-four million people currently infected with HIV need and a story of ingenuity, dedication, and humanity that will inspire the rest of us.
contents
Title Page
Copyright
Dedication
Epigraph
Cast of Characters
Preface
Part I: A Doctor, Two Patients, and Some Tests
Chapter 1: The Good Doctor in Denial
Chapter 2: A Visit with the Family Doctor
Chapter 3: Death Sentence?
Part II: The Disease, a Drug, and Its Industry
Chapter 4: Viral Trojan Horse
Chapter 5: A Weapon from the War on Cancer
Chapter 6: The Days of Acting Up
Chapter 7: Recognizing a Global Pandemic
Chapter 8: From the One Percent
Chapter 9: But, Doctor, I Don’t Feel Sick
Chapter 10: The Delta 32 Mutation
Chapter 11: Calling All Elite Controllers
Chapter 12: Treatment in Hiding
Part III: Treating the Berlin Patients
Chapter 13: The Second Diagnosis
Chapter 14: The Compassionate Use Exemption
Chapter 15: Three Deadly Diseases Move In
Chapter 16: The Comfort of Family and Strangers
Chapter 17: Timing
Chapter 18: Transplanting
Chapter 19: “Perhaps We Have Eradicated HIV”
Chapter 20: An Unexciting Recovery
Part IV: The Cure
Chapter 21: Trials
Chapter 22: Proof of Principle
Chapter 23: The Good Doctor in Court
Chapter 24: Not Even Surprising
Chapter 25: The Promise Kept
Chapter 26: A Child Cured—So What?
Chapter 27: Zinc Finger Snap
Chapter 28: The Abused, the Respected, the Relentless
Notes
Timeline
Acknowledgments
Index
