Locked away in a psychiatic hospital for the murder of his parents, no one believed Michael Tucker when he told them he was programmed by a genetic surgeon. Released into the world, he wants revenge. Dr Archer Howell has been experimenting on humans at Trans Cranial Applications, drilling the skulls of his patients and injecting drugs into their brain to create psychotic killing-machines. Isolated on an island and left to his own devices, Dr Howell is about to have a deadly visitor...

在养老院的老人，一个女儿读母亲的日记。这是在母亲的日记中提到的事件很快开始发生的女儿。