Eric Gorman returns with his wife Evelyn from a trip to the Orient collecting zoo animals, having killed a member of his expedition who happened one day to kiss Mrs. Gorman. On board ship Evelyn meets Roger Hewitt, who falls in love with her. After delivering his animals to the zoo, Gorman plots a way to dispose of Hewitt using one of his latest specimens, then continues using the zoo's non-human residents to do his beastly work.

Adam Larey becomes a fugitive from justice when he escapes after being blamed for a crime he did not commit. He wanders into the desert wastelands and joins an outlaw gang who prey on gold prospectors. Years later, he meets his wife and her gold-prospecting father as they have come there seeking their fortune, and not knowing the danger of the treacherous desert wastes, the poisoned-water holes and the outlaw bands of marauders who roam the desert in search of the gold found by others. He comes to their aid and, eventually, manges to clear his name of the false charge against him.

Someone is murdering the cast and crew of a new Hollywood movie, and the leading lady may be next. As a police detective locks down the lot and refuses to let anyone leave, the studio’s publicity head and his secretary attempt to solve the murders themselves.