Perfume creator Satin Chau is about to reveal her new designer scent, 'Puppy,' when she is cruelly struck down by a rare condition called anosmia, which robs her of her sense of smell and could even kill her. With time fast running out, she begins a frantic search for the only people who can provide the tissue-donations she desperately needs: her long-lost sisters, Corduroy and Velour.

In a poisoned world where sunshine kills, a hit squad from the Zyklor Corporation interrupts the testing of a matter replikator capable of duplicating living tissue for the purpose of extending human life. When the smoke clears, scientist Ludovic finds himself framed for murder and on the run from an exact duplicate... of himself. Joining forces with ex-lover Kat Moscow and cynical Detective Valiant, Ludovic follows the bloody path of destruction wrought by a monster with his face.

'Pleasantly plump' teenager Tracy Turnblad achieves her dream of becoming a regular on the Corny Collins Dance Show. Now a teen hero, she starts using her fame to speak out for the causes she believes in, most of all integration. In doing so, she earns the wrath of the show's former star, Amber Von Tussle, as well as Amber's manipulative, pro-segregation parents. The rivalry comes to a head as Amber and Tracy vie for the title of Miss Auto Show 1963.