Several old college friends converge at a mansion, ostensibly for a pleasant reunion. Larry Dann, the most easygoing of the bunch, comes to the conclusion that all is not well in the old dark house. For one thing, he's run across several people whom he's never met. For another, they all seem to be of a different time and place.

A psychiatrist treats a woman who is convinced that she turns into a killer leopard because of a family curse.

Tabitha, once the placid, gentle and devoted pet, adopts all the characteristics of a ferocious, wild animal following the murder of her mistress. The three guilty people are all trapped by the cat's power and each will come to untimely deaths of horrific proportions without anyone being able to solve the mystery that surrounds their brutal death.