Continuing after the first "Subspecies", a woman who has just become a vampire tries to escape the evil vampire, Radu, who seeks her as his love interest. But she has taken the vampire family's bloodstone, and now Radu must find her to get it back. While her sister comes to Romania to save her soul. It might be to late..

米歇尔仍然受制于邪恶的吸血鬼拉杜，她渴望被教导吸血鬼的技能。与此同时，她的妹妹贝基试图将她从他的邪恶魔爪中解救出来，这一次，她带来了一些帮助。

初出茅庐的吸血鬼米歇尔·摩根逃脱了她的主人拉杜·弗拉迪斯拉斯的控制。被一位名叫安娜的女士发现后，她被送往医院，医生声称能够治愈她的吸血鬼症。拉杜从米歇尔和她的朋友们带来的濒死中恢复过来，前往布加勒斯特跟随他的羽翼未丰。他参观了吸血鬼阿什的据点。Ash和他的门徒Serena密谋摧毁Radu，并利用人类Ana和博士的帮助。