“Lies in Plain Sight” tells the story of Eva and her blind cousin Sofia (Martha Higareda), who were inseparable as children, with Eva the loyal companion who helped Sofia through her tough adolescent years. When Eva suddenly commits suicide, Sofia rushes home to her father, Hector (Benito Martinez), and Eva’s parents, Marisol (Rosie Perez) and Rafael (Yul Vásquez), to find answers. But the more she delves into Eva’s life, questioning her past boyfriends Ethan (Chad Michael Murray) and Christian (Christoph Sanders), the more Sofia realizes that their childhood was actually filled with dark, disturbing secrets.

乖乖牌高中生簡與童年好友梅裏特重修舊好，並加入了他們的小團體。沒想到此舉引來珍的數學老師不滿，兩人之間產生衝突，最後導致老師遭學校解聘。某天，簡和梅裏特一行人闖進放學後無人的校園，卻發現一個喬裝成學校吉祥物的不明人士，已經鎖定他們展開追殺…