Jane Alexander's idyllic life in San Francisco is shattered when her beloved, elderly aunt is brutally murdered. But when her fiancé, Tom O'Donnell, becomes the main suspect, Jane must put aside her grief to aid the police before the chance at justice is lost forever.

A Nazi scientist, wanted as a war criminal, develops a spider serum that turns people into fascist Nazi zombies. A pair of investigators who have devoted their lives to hunting down Nazi war criminals set out to stop him.