Two young men, one in need of medical attention, are cryogenically frozen in the early 1960s. The two are preoccupied with the fact that the police are pursuing them to realise what they are doing. The next thing they know is that they are in a strange new world (thirty years on).

科学家、摇滚明星、漫画英雄、地球最后的希望Buckaroo Banzai和他的香港骑士们阻止邪恶的Lord John Whorfin为首的外星人回到PLANET 10，拯救地球的大冒险。