Helpless to stop a thief from stealing his father’s modest nest egg, Travis grows up blaming himself for his parents’ suicide. Becoming a priest who operates a highway confessional with his ambivalent brother, Michael, he offers sage advice to chosen sinners while raining death on unrepentant thieves. Into the world of this antagonistic duo comes Mary Francis, a deranged young woman with psychopathic tendencies who kills a thief who threatens to expose the decidedly un-holy siblings. Filled with gratitude, Travis invites the woman into their sacred world which begins a chain of carnage-laced events that threaten to destroy the brothers’ bloody, decades-long partnership.

When New Orleans Police Detective Danny Fisher stops a brilliant thief from getting away with a multimillion-dollar heist, the thief's girlfriend is accidentally killed. After escaping from prison, the criminal mastermind enacts his revenge, taunting Danny with 12 rounds of near-impossible puzzles and tasks that he must somehow complete to save the life of the woman he loves.