During World War II, an American major is captured by the Germans and thrown into a POW camp run by a sadistic Nazi officer, whose main pleasures are whipping the local female population and torturing prisoners. The major organizes an escape attempt using the camp's nubile female doctor as a hostage.

Following a bungled robbery, three violent criminals take a young woman, a middle-aged man, and a child hostage and force them to drive them outside Rome to help them make a clean getaway.