Derrick, a racially-confused Irishman raised in the hood by a black family is having the worst day ever. Determined to prove to his fed-up mother and would-be girlfriend that he's not a screw-up, he sets out to do one thing right (get some milk) and even that proves to be a challenge! Hilarious encounters with racist red-neck cops, local gangsters and 'flamboyant' pawn shop owners ensue, and along the way Derek shows that he can actually do things for others and maybe even get his own life together.

Victoria, Zenobia, Cleavon, and Phil are all friends approaching the age of 35 and struggling to build the families they've always dreamed of. While Zenobia is still looking for a man, Victoria is married to a man who doesn't want children. Cleavon, meanwhile, is too geeky to get a woman, and Phil is already married with children, but his wife is not very interested in being a mother. All four of them try to rectify their romantic lives and futures while their biological clocks tick away.

利奥（唐纳德·法森 Donald Faison 饰）是一个恪尽职守的快递员，一次失误中，他将一箱整整十公斤的高级可卡因错送给了无所事事的小混混布罗迪（迈克·艾普斯 Mike Epps 饰）与古奇（伍德·哈里斯 Wood Harris 饰），面对这天上掉下来的馅饼，两人做起了发财的美梦，他们找到了干毒品买卖的夏武（欧玛瑞·哈德威克 Omari Hardwick 饰），希望通过他将毒品脱手。
很快，这批毒品真正的主人波迪加（埃米里奥·瑞弗拉 Emilio Rivera 饰）就发现了事情的端倪，而毒品的负责人杰西（塞斯科·雷耶斯 Cisco Reyes 饰）更是记得如同热锅上的蚂蚁。而此时，早已经陷入了危险境地的布罗迪和古奇，却还在做着他们的春秋大梦。