故事讲述两个男人天生具有运用意志力操纵事物的超能力，当他们合力展现出这种能力时，被一个神秘机构的博士盯上，他们要逃离博士锲而不舍的恐怖追逐。

Mark Fisher disappeared from his home in a brilliant flash of blue light almost two years ago. His friend Seth Hampton was the last to see him alive. Now a string of grisly, violent murders leads Seth to believe that Mark is back, and something evil is living inside of him.

In need of creative inspiration, a professionally stagnant and hard-partying Los Angeles artist recklessly indulges in a series of drug binges. As the narcotics fly out of control, so does her newfound and inexplicable, yet unquenchable, craving for blood.