In the Tuscan countryside at the end of the 19th century, Pietro, the shy son of a tyrannical landowner, falls in love with Ghisola, a peasant girl with no family. His father has her sent away. Years later, the two meet again: still in love with her, Pietro would like to marry her, but she has become the mistress of a married man.

An epileptic 12-year-old girl, Pippi, is hospitalized in the psychiatric ward instead of the neurological ward, due to an administration error. Out of this mistake begins the difficult journey towards being cured.