Those who have interfered with the Tomb of Ra-Antef are in terrible danger. Against expert advice, American showman and financial backer of the expedition, Alexander King, plans a world tour exhibiting this magnificent discovery from the ancient world but on the opening night the sarcophagus is void of its contents. The mummy has escaped to fulfill the dreadful prophesy and exact a violent and bloody revenge on all those who defiled his final resting place.

一位太空救援專家和他的搭檔捲入了一群犯罪分子的行動，他們意圖偷走一顆由藍寶石製成的小行星，並將其撞向月球，然後將其取回。他們唯一能夠將小行星帶到不引起注意的地方是遙遠的礦區。但首先他們必須擺脫這名礦工。然而他們不知道的是，礦工的姐姐也僱用了同一支救援隊來幫助她尋找她的弟弟。

An eclectic group of characters set sail on Captain Lansen’s leaky cargo ship in an attempt to escape their various troubles. When a violent storm strikes, the ship is swept into the Sargasso Sea and the passengers find themselves trapped on an island populated by man-eating seaweed, giant crabs and Spanish conquistadors who believe it’s still the 16th century.

根据1940年同名影片改编：洞穴人杜马克被他的原始人部落驱逐，然后他在海岸边的另外一个部落里暂时落脚，但很快也被驱逐。因为很想念他，他的女人中的一个开始寻找到他并和他一起流浪，他们就像夫妇一样共同面对各种巨型怪物以及火山喷发等等其他的突如其来的危险。