Three beautiful young women are tricked and seduced by Lord Isherwood. When their plan for revenge accidentally kills him, the Lord's Gypsy protector Natasha places a curse on the three, putting them into a hundred-year sleep. 100 years later, the three are awakened when the American descendants of Lord Isherwood come to visit the family estate. The young ladies want nothing more than to get on with their lives and make up for lost time, but Natasha is not yet ready to let them leave.

In 1957, insurance investigator George Lazarus is tasked with interviewing twelve employees of the Deadly Sin Cigarette Company when his firm receives a suspicious insurance claim. He learns that all twelve had been let go after contracting mysterious illnesses, but before he can report back, Lazarus goes missing without a trace. After his disappearance, his fiancée Bethany and his friend Chip set out to find him - but what they uncover may actually signal the end of the entire human race.

Young girls are disappearing in and around the Mary Magdalen Halfway House for Troubled Girls.