On the Western frontier, the Pink Panther is a traveling vendor of pep pills. He unwittingly sells some pills to a frail criminal, who gains the strength to rob every bank in a nearby town! Thus, the panther is in as much trouble with the law as the robber and must act to apprehend the scoundrel.

When the Pink Panther tries to promote his drink with a series of signs, the starry dot atop the "i" in "pink" gains a mind of its own and, to frustrate the Pink Panther, turns green. Infuriated, the panther tries to eradicate the green dot, only to find that the dot has a guardian - another green dot of a much larger size.