When young art gallery owner and mother Kayla Anderson finds herself drowning in work and in need of help planning her daughter Kerry's big upcoming Sweet Sixteen bash, she hires pretty, spirited party planner Lindy Shores to help out, having no clue that Lindy is unstable and recently murdered her husband, and will stop at nothing to make Kerry a daughter of her own.

Lonnie, a crop duster pilot, must lead a mismatched group of survivors to escape the deadly zombie horde after an experimental chemical, intended to control the invasive kudzu vine, transforms the citizens of Charleston, MS into zombies.