Three gay roommates must find a fourth to share their flat after blowing their rent on a stripper who won't strip. In walks tall, sexy Lucas, the answer to their current problem and more than one of their dreams. But when they return home one night to find Lucas dead, and each tells his own real or imagined story about his relationship with Lucas, and they discover that they all had reasons to do him in.

当喜剧遭遇谋杀时，第一守则是将观众注意从暴力和恐怖中转移开。"Chuecatown"将视角放在谋杀的旁观者——一群健壮和八婆的同志身上，不同人的不同反应营造出了奇妙的化学效果。
在马德里的Chueca小区，老妇人一个一个被杀害。当地警方对此束手无策，包括一个退休探长和她的同志儿子。其实凶手是当地的地产经纪人Victor。Victor狂热的追逐“净化”Chueca小区，他希望把老人和丑八怪全部清洗出去，只留下年轻、漂亮、身材姣好的同志居住。
一对同志因为继承了死去女邻居的房子搬入了Chueca小区。Leo和Rey并不符合Victor的入住指标，而且Rey的难缠的老妈Antonia也过来探访，Victor的必杀名单又多了三个目标。Antonia绝不是普通意义的慈母，她让Leo和Rey的的世界水深火热。内有老妈捣乱，外有杀手索命，内外交困的Leo和Rey必需夹缝求生...