Roommates Prasath and Balaji are both in love with Selvi. However, life takes an ugly turn when Balaji dies and Selvi is forced to marry Prasath's father.

The film tells the story of Chandru, a singer who is touring Singapore with his band where he meets his love interest Sona only to find that she is terminally ill. The movie takes a turn when Chandru finds out about Sona’s cancer and decides to grant her final wish of performing on stage with his band. Ninaithale Inikkum was filmed around various locations in Singapore such as Paya Lebar Airport, Mount Faber, Orchard Towers and the Singapore River.

Chandram and Ranjani are in love with each other, but when their parents go against their union, they decide to commit suicide by jumping from a cliff. Unfortunately, Ranjani loses her life instantly but Chandram survives, and becomes a dance master.