Toby and Butch are a couple of bumbling crooks who get a truck driving job hauling insecticide from Italy to France. Unbeknownst to the clueless duo, they're really smuggling guns. A group of equally inept mobsters try to steal the guns to no avail.

Lucky Luke becomes the Sheriff of Daisy Town and runs out all the criminals. Then the Dalton brothers arrive and try to get the Indians to break the peace treaty and attack the town.