Sammy Hogarth, a vaudeville comedian who now has his own TV show, is a ruthless egomaniac who demands instant obedience from his staff and heaps abuse on those in lesser positions than his. His most vituperative behavior, however, is reserved for his weak-willed brother, Lester, whom Sammy has hired as his assistant but whom he really uses as his whipping boy.

THE LOST SKELETON RETURNS AGAIN takes on a whole new series of clichés, primarily drawn from those low budget adventure epics -- rich in potted ferns and stock footage -- that thrived on cheap back lots from the early 30s to the late 50s. It also wanders beyond the narrow confines of jungle pictures, parodying everything from gangster movies to those Mondo films of the 1960s, with their salacious native dances.

李小龙1969年在影片《Marlowe》（《马劳》中译《丑闻喋血》）中扮演一名来自东方的黑社会杀手，后坠楼身亡。主角神探马劳是由李小龙的功夫弟子詹姆斯·加纳担当。

南方战败后，南方老兵奥迈拉西行，加入苏族，娶了妻子，拒绝成为美国人，但苏族对美军作战时，他必须选择一方站队。

马戏团主任艾蒙多（里卡多·蒙特尔班 Ricardo Montalban 饰）收留并保护了一只孤苦无依的猩猩，取名凯撒（罗迪·麦克道尔 Roddy McDowall 饰）。在艾蒙多无微不至的关怀下，凯撒渐渐长大，它和“父亲”艾蒙多之间的关系十分亲密。
一场病毒的肆虐让猫和狗在地球上绝迹了，失去了最忠诚的朋友们，需要动物们陪伴的人类将目光转向了和他们极为相像的猩猩，就这样，饲养猩猩当做宠物成为了新的时尚。然而，人类的残暴本性使得这些原本温顺善良的猩猩们生活苦不堪言，它们被折磨虐待，永远的失去了自由。终于，猩猩们决定不再忍耐，在凯撒的带领下，它们英勇起义，发誓定要推翻人类的压迫和统治。