Dr. Eugene Ferguson (Cary Grant), a renowned American brain surgeon, and his wife Helen (Paula Raymond) are vacationing in Latin America when a revolution breaks out. They are taken against their will to the country's dictator, Raoul Farrago (José Ferrer), who urgently needs a life-saving operation.
Over the next few days, while Ferguson trains assistants for the delicate operation, he witnesses various acts of brutality by the regime, especially by Colonel Adragon (Ramón Novarro), but his Hippocratic Oath compels him to do his best.
Roland Gonzales (Gilbert Roland), the rebel leader, kidnaps Helen to pressure her husband into making a fatal surgical "mistake." His message to Ferguson is intercepted by Isabel Farrago (Signe Hasso), the patient's wife, and the operation is a success. Helen is released unharmed when Farrago dies soon afterwards and his government is overthrown.

At fictitious Tait University in the Roaring 20's, co-ed and school librarian Connie Lane (June Allyson) falls for football hero Tommy Marlowe (Peter Lawford). Unfortunately, he has his eye on gold-digging vamp Pat McClellan. Tommy's grades start to slip, which keeps him from playing in the big game. Connie eventually finds out Tommy really loves her and devises a plan to win him back and to get him back on the field.

Rich kid Danny Churchill has a taste for wine, women and song, but not for higher education. So his father ships him to an all-male college out West where there's not supposed to be a female for miles. But before Danny arrives, he spies a pair of legs extending out from under a stalled roadster. They belong to the Dean's granddaughter, Ginger Gray, who is more interested in keeping the financially strapped college open than falling for Danny's romantic line. At least at first...

Penny Morris and Tommy Williams are both starstruck young teens but nobody seems to give them any chance to perform. Instead, they decide to put up their own show to collect money for a summer camp for the kids.

Married songwriters almost split up while putting on a big show.

Three completely different stories are told through dance.

Mickey Moran, son of two vaudeville veterans, decides to put up his own vaudeville show with his girlfriend Patsy Barton. But child actress Rosalie wants to make a comeback and replace Patsy both professionally and as Mickey's girl.

Americans Jeff and Tommy, hunting in Scotland, stumble upon a village - Brigadoon. They soon learn that the town appears once every 100 years in order to preserve its peace and special beauty. The citizens go to bed at night and when they wake up, it's 100 years later. Tommy falls in love with a beautiful young woman, Fiona, and is torn between staying or going back to his hectic life in New York.