Five years after his father's murder by a drug cartel, former officer Wu Zhenfeng reappears as a wanted suspect, earning the nickname "Addict Lord." Now a narcotics officer, his former best friend Chen Yu is determined to uncover the truth behind Wu's actions. As their paths collide, a high-stakes game of loyalty, deception, and hidden motives unfolds.

该剧讲述了一名奇女子由牡丹培育而起，终达济民救世、帮扶天下的传奇励志故事。
商户之女何惟芳（杨紫 饰）与雅冠长安的蒋长扬（李现 饰）相识后，两人组成了匠人与投资人的组合。凭借培育稀世牡丹的高超技能和过人的经商头脑，何惟芳带领一众命运坎坷的女性共同经营花坊，过关斩将，在女子本弱的偏执沉疴中博得一席天地。随着何惟芳与蒋长扬的渐渐相熟，她发现这位一身骂名的“天下第一贪官”实则是外浪内纯、心怀天下的国之利刃。在亲历底层之苦、另悟牡丹之用后，何惟芳决心转型利民实业。
最后她经历九死一生，突破了自我，凭其陶朱之术与玲珑之心，帮蒋长扬成功平定了叛乱，有情人双双隐退天地间。
剧集改编自意千重的同名小说。