When the hospital she works at is transported to the moon, medical student Martha Jones joins forces with The Doctor to hunt down an alien fugitive before the oxygen runs out

博士的塔迪斯被追尾，肇事船居然是泰坦尼克号。原来一家外星旅游公司仿照泰坦尼克号制造了一艘巨大的泰坦尼克号宇宙飞船。但是飞船却连续遭遇不幸：防护罩被毁，装上陨石群，船长死去，服务机器人嗜杀成性……。

本集讲述博士和泰勒回到当代的伦敦渡过圣诞节。然而，外星人希克拉库斯（Sycorax）却在这时入侵地球。最终，因重生过后昏倒的博士及时醒来，击退入侵者。在英国，这集有980万人收看，并取得正面的评价。
这是扮演第十任博士的大卫·田纳特首次出演整部《神秘博士》剧集。此前，他在《背水一战》的最后一幕出场。同时，这是《神秘博士》首部的圣诞特辑。自此以后，BBC One每年均会制作一部圣诞版的《神秘博士》剧集。

失去了罗斯的博士正在心灰意冷，而正在举行婚礼的多娜却被突然传送到塔迪斯里。博士带坏脾气的多娜返回地球，却被一群外星机器人追杀，塔迪斯上演了一场公路飚车。后来博士发现多娜身上带有异常含量的Huon粒子，而该粒子来源于上一代宇宙霸主。而博士的母星加利弗雷在宇宙中崛起时，已经消灭了所有的Huon粒子。最终博士揭开了一个藏于地球40亿年的秘密。

Episode 1: The Eleventh Hour
Episode 2: The Beast Below
Episode 3: Victory of the Daleks
Episode 4: The Time of Angels
Episode 5: Flesh and Stone
Episode 6: The Vampires of Venice
Episode 7: Amy's Choice
Episode 8: The Hungry Earth
Episode 9: Cold Blood
Episode 10: Vincent and the Doctor
Episode 11: The Lodger
Episode 12: The Pandorica Opens
Episode 13: The Big Bang

在伦敦的一辆公交车上，博士遇到了珠宝大盗克里斯蒂娜夫人，但情况急转直下，公交车意外驶向一个类似沙漠的星球，而致命的“蜂群”在那等待着他们。

The Ood have given a warning to The Doctor. The Master is returning yet that is not the biggest threat. A darkness is coming which brings with it The End of Time.

The Doctor faces the end of his life as the Master's plans hurtle out of control. With the sound of drums growing louder, and an ancient trap closing around the Earth, the Doctor and Wilf must fight alone. But sacrifices must be made, and the deadly prophecy warns: "He will knock four times."