1966年，吉他大师Eric Clapton为了继续施展在布鲁斯方面的抱负，离开了先前的乐队，跑到伦敦找到John Mayall的Bluesbreakers一起合作，仅仅数月之后，Clapton就离开了Bluesbreakers，组建了Cream。然而，就是在这样一次短暂的合作期间，却诞生了一张伟大的专辑，这张专辑从一开始就以Clapton的吉他为卖点，在伦敦引发了对Clapton的崇拜热潮，有fans打出了“Clapton是神！”的标语，吉他之神从此也就成了Clapton的绰号。
这张专辑在布鲁斯摇滚历史上的地位可谓十分显赫，被认为在很多方面创立了布鲁斯摇滚的标准。专辑在该年度进入UK专辑排行榜的前十。
这张专辑在滚石杂志选出的500张历代最强专辑中排名第195位。

这张专辑被认为是Eric Clapton一生中最强的专辑之一，而且也被认为是布鲁斯摇滚的巅峰之作。是Eric在解散了Cream之后，和键盘手obby Whitlock，贝司手Carl Radle，鼓手Jim Gordon，以及吉他手Duane Allman组成的Derek and the Dominos推出的。关于Clapton解散Cream的原因，据说是由于他听了The Band的作品，觉得布鲁斯才是自己的方向。

这张专辑在1970年推出的时候，市场并不十分看好（Billboard第16，在英国甚至没有上榜），但经过岁月的沉淀之后，这张专辑的价值越来越得到人们的肯定，在1996年再版之后，2004年又发行了SACD版。

本专辑在滚石杂志评出的500张历代最强专辑中排名第115位

Released in conjunction with Eric Clapton's autobiography, COMPLETE CLAPTON provides the soundtrack to the original guitar hero's decades-spanning journey. Over the course of two discs, this collection tracks Clapton's progress from the ground-breaking psychedelic blues-rock of Cream and the short-lived supergroup Blind Faith, through his Duane Allman collaboration, Derek & the Dominos, and on to his prolific solo career.
Clapton is personally responsible for a huge chunk of the classic-rock canon, and it's all included here. The primal crunch of Cream's "Sunshine of Your Love," the bluesy riffarama that is Derek & the Dominos' evergreen "Layla," the country-tinged twangfest "Lay Down Sally"--you name it, COMPLETE CLAPTON has it. This set doesn't stint on later material, either, like Clapton's Robert Johnson tribute and a duet with J.J. Cale. With the possible exception of his very early work with John Mayall, there's nary a career highlight missed on this comprehensive anthology.

Music legend Eric Clapton has reunited with famed producer Glyn Johns for his forthcoming 23rd studio album I Still Do, set for release on May 20, 2016 on his Bushbranch Records/Surfdog Records. Clapton and Johns who has also produced albums for The Eagles, The Rolling Stones, Led Zeppelin and The Who most famously worked together on Clapton's iconic Slowhand album, which is RIAA-certified 3x-platinum and topped charts globally. The 12-track record includes some original songs written by Clapton. This album follows his last release, the 2014 chart-topping Eric Clapton & Friends: The Breeze, An Appreciation of JJ Cale.