剧中讲述美国300年前，女巫终结了对她们的迫害但条件是她们得成为国家的战力。剧集背景设置在现代，现今年轻女性当到达18岁时会被征召，然后送入一处叫塞勒姆要塞/Fort Salem的地方学习魔法战斗。
主角是三个少女，她们身处的这个世界所重视的性别及给予的权力都是反传统的，少女们将会是面对恐怖份子的防线，用的不再是枪械，而是超自然能力。

Without a military nor a home, Abigail, Tally, Raelle and Scylla seek protection alongside the Dodger community in the Cession — but laying low and staying out of trouble has never been their strong suit. With witch hunters working against them from inside the White House, our heroes must call upon ancient forces in the final battle for their right to exist.