After an aging voodoo priestess dies, her arrogant son Willis Daniel's believes he is next in line to lead. He is outraged when Lisa, his mother's adopted apprentice is chosen as the leader. Willis seeks revenge by reviving the African prince Blacula — but soon finds that he cannot control him.

一个18世纪的非洲王子在访问特兰西瓦尼亚（Transylvania）时被变成了吸血鬼。两个世纪后，他从棺材里爬起来，袭击洛杉矶的各种居民，然后遇到了蒂娜（Tina），他相信她是他已故妻子的转世。