2013年，突变的虫草菌肆虐美国，真菌将人类宿主变成了攻击性超强的吃人怪物。20年后，人类文明已面目全非，幸存者只能生活在治安隔离区。一天，乔尔（佩德罗·帕斯卡 饰）和泰丝（安娜·托芙 饰）接了一个赏金任务，要护送一个14岁的女孩艾莉（贝拉·拉姆齐 饰）去反抗组织火萤的研究基地。可他们不知道的是，女孩身上隐藏着一个关系到人类文明延续的秘密……

Based on one of the greatest video game series of all time, Fallout is the story of haves and have-nots in a world in which there’s almost nothing left to have. 200 years after the apocalypse, the gentle denizens of luxury fallout shelters are forced to return to the irradiated hellscape their ancestors left behind — and are shocked to discover an incredibly complex, gleefully weird and highly violent universe waiting for them.