Sideways is the story of two friends-Miles and Jack-going away together for the last time to steep themselves in everything that makes it good to be young and single: pinot, putting, and prowling bars. In the week before Jack plans to marry, the pair heads out from Los Angeles to the Santa Ynez wine country. For Jack, the tasting tour is Seven Days to D-Day, his final stretch of freedom. For Miles--who has divorced his wife, is facing an uncertain career and has lost his passion for living-the trip is a weeklong opportunity to evaluate his past, his future and himself.
A raucous and surprising novel filled with wonderful details about wine, Sideways is also a thought-provoking and funny book about men, women, and human relationships.

1967年，在非洲的扎伊尔莫他巴河谷，美国的雇佣军兵营中被一种突如其来的疾病肆虐，死亡人数不断攀升。军医抽取感染血样离开后，整个军营被炸弹摧毁，附近树林中的白脸猴发出阵阵惊叫声……
直到90年代，一个美国年轻人在非洲扎伊尔捕捉到一只小白脸猴，并带回国出售。由于不合买主要求，年轻人将猴子放生，之后一种新型疾病在旧金山的香柏溪镇上蔓延。美国传染病研究所上校军医山姆（达斯汀·霍夫曼 Dustin Hoffman饰）接到消息，与妻子（蕾妮·罗素 Rene Russo 饰）及同事立刻展开研究和救治工作。由于疾病传染性极高，政府紧急出动军队封锁镇子，想要逃离者格杀勿论。此时，有一批保密的染毒血清被送来，但山姆等一群人研究发现，这批血清能救治1967年的疾病，却对如今变异后的病毒毫无作用。不久，山姆的妻子不幸被感染，生命垂危中时，政府也作出决定，准备投放炸弹摧毁整个镇子，以此消灭病毒。时间迫在眉睫，山姆查出了病毒的来源，他必须抢在投弹前找到原始病毒携带者。

无论你是否看过希区柯克的心理惊悚代表作《迷魂记》，都会为这部重述作品中饱含的神秘与乐趣所着迷。全片素材都来自以已有的电影电视作品，追溯多种视觉媒介对旧金山这座城市的描摹轨迹，整合起散落素材重塑为复杂有序的影像。笼罩着诡谲、浪漫和悬念，升腾的绿色雾气蒙住带有浓重怀旧气息电影画面，邀观众一起再度跌入狂热幻梦的怀旧领地。