Molecular Biology, 5th Edition
豆瓣
Robert F. Weaver
简介
Molecular Biology, 5/e by Robert Weaver, is designed for an introductory course in molecular biology. Molecular Biology 5/e focuses on the fundamental concepts of molecular biology emphasizing experimentation. In particular author, Rob Weaver, focuses on the study of genes and their activities at the molecular level. Through the combination of excellent illustrations and clear, succinct writing students are presented fundamental molecular biology concepts.
contents
About the Author iv
Preface xiii
Acknowledgments xvii
Guide to Experimental Techniques in Molecular Biology xix
PART I Introduction
1 A Brief History 1
2 The Molecular Nature of Genes 12
3 An Introduction to Gene Function 30
PART II Methods in Molecular Biology
4 Molecular Cloning Methods 49
5 Molecular Tools for Studying Genes and Gene Activity 75
PART III Transcription in Bacteria
6 The Mechanism of Transcription in Bacteria 121
7 Operons: Fine Control of Bacterial Transcription 167
8 Major Shifts in Bacterial Transcription 196
9 DNA–Protein Interactions in Bacteria 222
PART IV Transcription in Eukaryotes
10 Eukaryotic RNA Polymerases and Their Promoters 244
11 General Transcription Factors in Eukaryotes 273
12 Transcription Activators in Eukaryotes 314
13 Chromatin Structure and Its Effects on Transcription 355
PART V Post-Transcriptional Events
14 RNA Processing I: Splicing 394
15 RNA Processing II: Capping and Polyadenylation 436
16 Other RNA Processing Events and Post-Transcriptional Control of Gene Expression 471
PART VI Translation
17 The Mechanism of Translation I: Initiation 522
18 The Mechanism of Translation II: Elongation and Termination 560
19 Ribosomes and Transfer RNA 601
PART VII DNA Replication, Recombination, and Transposition
20 DNA Replication, Damage, and Repair 636
21 DNA Replication II: Detailed Mechanism 677
22 Homologous Recombination 709
23 Transposition 732
PART VIII Genomes
24 Introduction to Genomics: DNA Sequencing on a Genomic Scale 759
25 Genomics II: Functional Genomics, Proteomics, and Bioinformatics 789
Glossary 827
Index 856
