The bandit Pratt, looking for Tim, who is responsible for the death of his two sons, attacks a caravan killing all the passengers. Harry, the vagabond, after having robbed the dead, casually meets Tim and they become friends. Running away together from Pratt, they reach Harry's farm, but their hiding place is soon discovered.

Sartana, bounty hunter and gunfighter, witnesses the robbery of a shipment of gold. He finds his way into town where he meets with a lot of suspicious stares from the locals. He also meets with Samuel Spencer, who seems to own the company in this company town. The gold shipments are being stolen, so Spencer agrees to hire Sartana to protect the next gold shipment. Numerous dull-witted villains make attempts on Sartana's life, but he survives. Eventually, Sartana's nemesis Sabbath (he of the white coat and parasol) rides into town. With a showdown inevitable, Sartana and Sabbath square off to settle the score.

在目睹了一场残酷的大屠杀后，传奇英雄萨尔塔纳准备进行一些调查。印第安溪小镇上几乎每个人都急于买下谋杀案受害者留下的财产，其中一人很可能是谋杀案的幕后黑手。警长本人并没有受到怀疑，所以萨尔塔纳必须自己找出罪魁祸首。