Three psychotic murderers escape from a mental institution and stalk women in Los Angeles.

Set in the sordid underworld of drug trafficking and prostitutes, this story involves Charlie Smith, private eye, whose job it is to find Carrie Friskine and fast! Carrie, a cat burglar, has ripped off the ring-leader of a drug racket and now he's after her blood.

越战老兵埃迪误触地雷四肢尽失，幸得天才外科医生移植新肢。岂料疯狂迷恋其未婚妻的助手暗中调换DNA药剂，使埃迪异变成嗜血巨怪。