家住岛根县安来市的饭田布美枝（松下奈绪 饰）出生在一个商人家庭，与姐妹们相比她是如此的不起眼，所以心里有着种种的执拗和自卑。在昭和35年的秋天，她通过相亲认识了名不见经传的漫画家村井茂（向井理 饰）。过惯了富裕日子的布美枝，婚后自然被村井家的赤贫所困扰。当然在各种龃龉和挫折过程中，她咬着牙坚持下来，并且鼓励好不容易找到前进方向的丈夫朝着既定的目标前进。一对平凡的夫妻，走过战后最苦难的岁月，见证着一个战败国家的顽强复兴，也迎来了他们人生的辉煌……
本片根据漫画家水木しげる（《墓场鬼太郎》）的妻子武良布枝的自传改编。

Set in Tokyo in 1940, the peaceful life of the Nogami Family suddenly changes when the father, Shigeru, is arrested and accused of being a Communist. His wife Kayo works frantically from morning to night to maintain the household and bring up her two daughters with the support of Shigeru's sister Hisako and Shigeru's ex-student Yamazaki, but her husband does not return. WWII breaks out and casts dark shadows on the entire country, but Kayo still tries to keep her cheerful determination, and sustain the family with her love. This is an emotional drama of a mother and an eternal message for peace.

Fifty years of war between the Great Eastern Federation and Europa - now merged as Eurasia - have taken their toll on planet Earth. As a result of the use of biological, chemical and nuclear weapons, much of Earth has become uninhabitable and people have become prey to new diseases. Professor Azuma's "neo-cell" project, which is supposed to be the answer to mankind's hardships, becomes a nightmare come true when mutants spawned from the experiment escape and declare war on the human race. Azuma's son Tetsuya, who was killed during the previous war, is reborn into the cyborg Casshern as mankind's last hope against the new mutant threat. This live-action sci-fi movie based on a 1973 Japanese animé of the same name.