Five jaded young friends foolishly dabble in the dark arts and unleash Anubis, the Egyptian God of the dead, on an unsuspecting New England island. As the body count rises, the survivors must figure out a way to defeat the powerful creature as they fight not only for their lives, but for their very souls.

The "Overlook Animal Research Laboratory" has long been working on genetic engineering without any trouble. That all changes one night when two would be animal liberators set free a test rabbit, not knowing that the bunny's genes have gone haywire.