Luciana is a factory worker married to the love of her life. She is living the simple and quiet life she’s always desired: she works and she is deeply in love with her husband Stefano, even if he doesn’t always have a job and they both need to struggle to keep on going. They are happy and always on each other’s side, but shortly after she finds out she’s pregnant, she gets fired and her world starts falling apart. After having tried to have a baby for years, the joy of impending motherhood lasts only a few months. Begging for help but with no one ready to listen to her, completely desperate and shattered, Luciana decides to kidnap the managing director of her former company, asking for the justice she deserves.

Lucia and Maria are two best friends, who have known each other from the beginning of their life, but have very different tastes and behaviors. Lucia is done with men, Maria, on the contrary, cannot be without one. One night, the perfect man shows up in Maria's bed: handsome, sensible, mature and passionate.The next morning brings up misunderstandings and lies which make the two friends split up and take a break for themselves. Maybe that young man met by chance is really the one every woman is looking for, because with his simple theories he manages to paint the perfect picture of the two women's lives.

高速公路上的猫源于一句谚语，用来形容注定不会长久的事情。乔凡尼（安东尼奥·阿尔巴内斯 Antonio Albanese 饰）是那种典型的知识分子，每天读书看报认真思考人生，始终相信人和人之间能够拥有真正的信任，互相融合。莫妮卡（宝拉·柯特莱西 Paola Cortellesi 饰）和乔凡尼恰恰相反，身为超市收银员的她每天都要应付不同肤色和不同人种的客人们，常常感到焦头烂额，对人和人之间的沟通感到非常悲观。
上帝开了一个小小的玩笑，这两个八竿子打不到一起的人，他们的儿女却被牵上了红线走到了一起，得知了这一段恋情的两人由衷的希望它能像高速公路上的猫那样，尽早结束。

结婚15年的夫妻瓦莱里娅和尼古拉协议分手。既然热情没了，还不如早早结束关系，他们不想最后变成一起坐在客厅看电视的朋友。两人谈好一切，包括赡养费、房子产权、子女共同监护权。他们正要把消息告诉三个孩子之前，两人都得到梦寐以求的海外工作机会。
好脾气的瓦莱里娅本来要放弃，但忽 然发现尼古拉和美丽小护士有一腿。她决定不要自我牺牲，立刻接受新职位。父母都准备去海外工作，三个孩子的监护权要归谁？如果爸妈不能做决定，那么孩子就自己选边站。离婚夫妻尼古拉和瓦莱里娅为了监护权而各自出奇招，然而跟一般人不同的是，他们要把监护权做给对方，想尽办法让孩子选择跟对方一起生活！
在这之前，尼古拉和瓦莱里娅对孩子总是百依百顺，然而时局变了，马迪亚、维奥拉和朱利埃托发现爸妈竟然性情大变，竭尽一切所能让他们的日子过不下去！

一个是才华洋溢的逗比女建筑师，一个是魅力四射的餐厅暖男老板。她喜欢男人，而他也是，女的近来人生坎坷 命途多舛，男的离婚出柜 不敢把真相告诉孩子，女的狗血的喜欢上男的 男的说我们是BFF...