Having fled to Mexico from the U.S. many years ago for killing his father's murderer, Martin Brady travels to Texas to broker an arms deal for his Mexican boss, strongman Governor Cipriano Castro. Brady breaks a leg and while recuperating in Texas the gun shipment is stolen. Complicating matters further the wife of local army major Colton has designs on him, and the local Texas Ranger captain makes him a generous offer to come back to the states and join his outfit. After killing a man in self-defense, Brady slips back over the border and confronts Castro who is not only unhappy that Brady has lost his gun shipment but is about to join forces with Colton to battle the local raiding Apache Indians.

Songwriters Calhoun and Harrigan get Katie and Lily Blane to introduce a new one. Lily goes to England, and Katy joins her after the boys give a new song to Nora Bayes. All are reunited when the boys, now in the army, show up in England.

巴克是一只骨骼壮硕身材强壮的狗，本来在大法官家里过着养尊处优的生活的它，被园丁偷走，卖到了严寒的阿拉斯加，成为了雪橇犬。巴克坎坷的命运并没有就此终结，之后，它又辗转经历了好几个主人，他们残暴而又冷酷的对待巴克。不仅如此，巴克在狗群中也为了保住自己的地位而经历了巨大的挑战。
这一次，约翰（克拉克·盖博 Clark Gable 饰）成为了巴克的新主人，幸运的是，约翰是一个善良的男人，他不仅非常温柔的对待巴克，还治好了它伤痕累累的身体。随着时间的推移，一人一狗之间产生了坚实的友谊。然而，在一场意外中，巴克被印第安人杀死了，愤怒的巴克失去了理智，它要为自己的主人报仇。