Mrs. Topper's friend Mrs. Parkhurst has convinced Mrs Topper to file for a divorce from Cosmo due to the strange circumstances of his trip with ghost Marion Kirby. Marion comes back from heaven's door to help Cosmo again, this time only with dog Mr. Atlas. Due to a strange behavior of Cosmo, the judge refuses to divorce them, so Mrs. Parkhurst takes Mrs. Topper on a trip to France where she tries to arrange the final reasons for the divorce. With help of a gold-digging French baron, Marion takes Cosmo to the same hotel to bring them back together and to get her own final ticket to heaven, but the whole thing turns out to be not too easy.

This Universal programmer was based on a Collier's Magazine story by journalist Quentin Reynolds. This story in turn was ostensibly based on a true incident, in which a gangster "returned from the dead" to save an innocent young man from the electric chair. The nurse of the film's title is Katharine McDonald, who falls in love with her prizefighter-patient Lee Burke as he recovers from a beating received in a fixed prizefight. Katharine must fend off the advances of criminal attorney John Dodge, another patient who also loves her and becomes jealous of Lee. But when Lee is framed for the murder of his disgruntled manager, Slice, by a henchman of the fight-fix leader, Joe Largo, Dodge takes on his defense and works with Katherine to discover the real killer. Convicted and sentenced to death, Burke is about to walk the "last mile", as Katharine encourages mortally wounded Largo to a deathbed confession.

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