The brother of a notorious outlaw is put in a charge of a stagecoach line way station in dangerous Apache territory. A stagecoach arrives at the station with a valuable box of cargo, and the outlaw brother soon shows up, though denying that he's planning to take the cargo box. Soon, however, rampaging Apaches attack the station, and the station manager, his brother and a disparate group of passengers and employees must fight them off.

Story follows a stagecoach ride through Old West Apache territory. On board are a cavalry man's pregnant wife, a prostitute with a broken heart, a Marshal taking in his prisoner Johnny Ringo, a crooked gambler, and the infamous Doc Holliday