In the questionable town of Deer Meadow, Washington, FBI Agent Desmond inexplicably disappears while hunting for the man who murdered a teen girl. The killer is never apprehended, and, after experiencing dark visions and supernatural encounters, Agent Dale Cooper chillingly predicts that the culprit will claim another life. Meanwhile, in the more cozy town of Twin Peaks, hedonistic beauty Laura Palmer hangs with lowlifes and seems destined for a grisly fate.

Novelist Hank Moody struggles to help raise his 13-year-old daughter, while carrying a torch for his ex-girlfriend Karen. His obsession with honesty and his self-destructive behavior are simultaneously destroying and enriching his career. . . all this in the city he loathes the most: Los Angeles.

该剧讲述25年前被困在红房间里的库珀被超自然力量释放回人间，当年双峰镇的居民早已衰老，而诡异的谋杀案件又出现了的故事。

Not long after they cross paths at an art gallery, architect Ray Reardon and hypnotically sensual Lena are married with children. But as strange incidents occur, Ray begins to realize he may not really know the woman he married.