Dean, a failed American writer, receives some unexpected news: his wife, who belongs to a wealthy family, has filed for divorce. Stunned, he decides to commit suicide. His initial attempt fails when he has second thought. But during a drunken blackout spent gambling he wins big and promises all the winnings to the man who can kill him...but they must possess a special playing card.

Girls of a corrupt orphanage are being sold by the sadistic matrons to a badly disfigured doctor. His sinister motive is to use the girls as guinea pigs in his experimental brain surgeries.