In Sierra Negra, graverobbers Barraza and Mendoza steal the coffin of Count Karol de Lavud, before heading to a hospital. Barraza sees a medallion upon the coffin's opening and demands more money from Mendoza. Meanwhile, Marta González, recovering from traumatic events, works as a nurse with Dr. Saldívar. When Barraza removes the wooden stake in order to steal Lavud's medallion, the vampire returns to life and begins a crime spree, hunting down Marta to marry her.

1661年，在墨西哥，阿斯塔拉（Astara）的维提利乌斯（Vitelius）男爵因巫术、招魂术和其他罪行被墨西哥宗教裁判所判处火刑。在他临死之际，男爵发誓要向宗教裁判所的子孙后代复仇。300年后，一颗曾在男爵被执行死刑之夜掠过天际的彗星再次降临地球，带来了男爵的化身：一个可怕的、食脑的怪物，他对宗教裁判官的子孙后代进行恐吓。

A pretty young Mexican girl returns to her hometown to make funeral arrangements for her beloved aunt, who has just died. Soon she begins to hear disturbing stories about the town being infested by vampires, and she eventually begins to suspect that her remaining aunt and the mysterious next=door neighbor may be involved.