Bruno Corazzari and his gang are in jail awaiting trial. They hire Fernando Sancho's gang to kill the only witness who then take all the passengers of a stagecoach hostage, in Richard Harrison's inn, because they are unsure which of them is actually the witness.

Rosario fue condenada injustamente por un robo cometido en el teatro donde trabajaba como secretaria del productor Gastón Leducq. Cuando sale de la cárcel, intenta demostrar su inocencia a Gastón, pero las cosas no suceden como ella esperaba.

Emma is a teenager when she is the victim of a terrible road accident in London, and needs psychiatric care after she suffers from resulting brain injury. Her mother, Silvia, confines her in the house, and Emma's personality becomes aggressive, leading to a regrettable series of violent deaths.

Steve McGowan has proposed to avenge the death of his father, murdered by one of the followers of Chief Miller. This engages the services of a famous gunslinger called Sabata and instructs him to kill Steve. The fate joins Steve and the Mexican bandit Leon Pompero, and together they decide to defeat the murderous gunman.