魔鬼卡车有巨大的车轮、钢铁车厢和超强功率，可以碾碎任何挡在它前进路上的东西!在荒无人烟的1-55地区，有一辆魔鬼卡车赋予这个名字新的意思，不只卡车是恐怖的，还有它的司机。两名大学生开车误入魔鬼卡车的通道上，他们要担心的不只是充满了被截肢的乡巴佬的酒吧，还有这辆魔鬼卡车和他的主人......

Matt Hobbs is a talented but unsuccessful actor. When estranged (and strange) ex-wife Beth dumps their daughter Jeannie on Matt, father and daughter have a lot of adjusting to do. His budding relationship with attractive production assistant Cathy Breslow is made complicated, while the precocious child is overly accustomed to getting her own way. Matt eventually faces the choice of family vs career in a particularly difficult way.