A millionaire philanthropist collects the famous Crystal Skulls trying to tap into their ancient powers. It is up to a team lead by a college professor whose father disappeared searching for the 13th skull to save the world when the first 12 skulls are united and reek havoc on the earth without the control of the 13th skull.

一个本地流浪汉发现一起针对美国的阴谋后，警长置之不理，并把他拘捕。当真相被掩盖，正义被泯灭的时候，需要五个杂牌英雄联起手来，挫败反叛者们的阴谋……

特种女兵布伦纳·贝克和伴侣迪伦在亚拉巴马州的荒山野林里徒步旅行，误入黑帮毒贩的老巢。迪伦被残忍杀害，布伦纳有幸逃生。这群残暴的毒贩没有想到的是，布伦纳作为美国陆军第75游骑兵部队的第一中尉，誓让他们所有人血债血偿。