Vint is in a troubled marriage. After taking a road trip with his wife they are abducted leaving him for dead and his wife missing. Months later he awakens from a coma, returns home and starts to get his life back in order. Mia his young sister-in-law moves in to take care of him as he recovers. After evidence comes forth and authorities have long given up. The two team up and return to the small town where his wife was last seen. They are led down a violent rabbit-hole where they might not find out the truth behind her disappearance.

一名孤独的拖车司机在路上被逃亡的银行劫匪撞上并劫为人质。劫匪带着他逃入亚利桑那的山中，警方紧追不舍。然而他们很快发现，山林里潜伏着更可怕的存在：嗜食人肉的怪物。如今，罪犯、警察与人质不得不放下对立，为了活过今夜而联手求生。