一颗流星坠入科尔佩珀动物园，释放出一种病毒，把动物们变成了流着口水的丧尸变种！格雷西，一只特立独行的小狼，与一只脾气暴躁、令人畏惧的山狮丹，以及一群争吵不休的动物组成了团队。但当整个动物园眼看就要被丧尸动物攻陷时，格雷西想出了一个计划，要让所有动物恢复正常，拯救动物园。这就是 “动物丧尸末日”！

A collaboration of computer-animated films which features new characters and old friends from the award-winning Fox network television series, "The Simpsons" and Dreamworks' feature film "Antz" The saucy, synthetic hostess, Phig, takes the viewers through Cyberworld 3D, a futuristic gallery of wild adventure and spectacular images. Trouble arrives in the form of three unwelcomed guests named Buzzed, Wired and Frazzled who are inadvertently destroying the environment's foundation, forcing Phig into a hilarious battle to save herself and Cyberworld 3D from total annihilation!