Anzu, Hiiragi, and Koume are three girls who attend the lively Hanamaru Kindergarten. There they have lots of adventures with their classmates and with Naozomi Tsuchida, their teacher who has just started working fresh out of school.

Yurie is just an ordinary middle school girl in the 1980's - until overnight she finds out that she is a Kami, or God, in the Shinto sense. When Yurie announces this fact to her best friend Mitsue, their classmate Mitsuri takes advantage of Yurie's new divinity to revitalize her family's dying shrine. Yurie is nicknamed Kamichu and now must go on with her godly duties while going to school and winning the heart of her crush, Kenji, while Mitsuri tries to replace her old shrine god Yashima with her.

A high school student named Yachi Haruaki receives a mysterious, super-heavy black cube from his father overseas. That night, Haruaki wakes up to a suspicious noise in the kitchen, and he discovers a fully naked female thief of rice crackers. The girl, Fear, is the first of several surprises that Haruaki receives.