Manhattan, 1996. All mental hospitals must cut their patient load by a third, and LaRue (Will Keenan) is sent out onto the streets with "chronic reading syndrome". He ends up at the Love Hotel (where most of the inmates are being held), and falls in love with a mute girl who's obsessive mother dominates her life. To top it all off, LaRue is given a roommate with Tourette's syndrome and is chased by a prehistoric worm that inhabits peoples bodies and mutates them.

A demented former lawyer uses autopsy equipment to kill off the teenagers who trespass on the long-abandoned asylum he inhabits. Filmed on location in an actual abandoned asylum.

A young woman wanders around New York City and stumbles across a number of strange characters and settings that represent the "underground" areas of the city. She sees stand up comedy in Central Park, a prostitution auction, a voodoo ceremony, an S&M club, and a number of very interesting performance artists. These are just a few of the sights and sounds of New York that she encounters.