《保重》是一部喜剧，讲述了一位女士（莱斯利·比伯饰）被车撞后从医院回到家，却发现没有人愿意照顾她的故事。在被她的姐姐（纳迪亚·达贾尼饰）、最好的朋友（马林·爱尔兰饰）和邻居（迈克尔·斯塔尔-大卫饰）拒绝后，她不情愿地请求前男友（托马斯·萨多斯基饰）帮助她。

Martin Best is a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin's blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he's all they’ve got.